Gait disorders are one of the most frequent symptoms encountered by neurologists. In neurological inpatients, more than 60% of gait disorders are diagnosed due to stroke, Parkinson’s disease, multiple sclerosis (MS), spinal cord injury (SCI) and spinal disorders. Walking deficits after damage to a particular neuroanatomical system are often variable and unspecific, which hinders accurate diagnosis and optimal treatment. Until now patient stratification for clinical trials and outcome prediction in neurological diseases, in particular for those in which multiple anatomical systems are affected (as in SCI or MS), is still poor and so there is an urgent need for a better characterization and understanding of these disorders. We established a gait lab with state of the art equipment. In close collaboration with the Department of Neurology of the University Hospital Zurich we will develop a comprehensive gait analysis approach for humans with neurological diseases and perform a systematic and comparative examination of neurological syndromes in which single and multiple neuroanatomical systems are affected. This will lead to a better understanding of the basic pathophysiological mechanisms underlying walking impairments in neurological disorders, thus, improving diagnosis, treatment, stratification and outcome prediction of patients.
For further information please contact: PD Dr. Marc Bolliger